An astrophysicist and a neurosurgeon walked into a room.

It may sound like the start of a horrible joke, but what a group of Italian academics came up with is a truly galaxy brain take: the structures of the observable universe, they claim, are startlingly similar to the neural networks of the human brain.

In a recent research published in the journal Frontiers in Physics, University of Bologna astronomer Franco Vazza and University of Verona neurosurgeon Alberto Feletti reveal the unexpected similarities between the cosmic network of galaxies and the complex web of neurons in the human brain. According to the researchers, despite being nearly 27 orders of magnitude distant in scale, the human brain and the makeup of the cosmic web exhibit similar levels of complexity and self-organization.

The brain contains an estimated 69 billion neurons, while the observable universe is composed of at least 100 billion galaxies, strung together loosely like a web. Both actual galaxies and neurons only account for about 30 percent of the total masses of the universe and brain, respectively. And both galaxies and neurons arrange themselves like beads on long strings or filaments.

In the case of galaxies, the remaining 70 percent of mass is dark energy. The equivalent in the human brain, the duo said: water.“We calculated the spectral density of both systems,” Vazza said in a statement about the work. “This is a technique often employed in cosmology for studying the spatial distribution of galaxies.”

“Our analysis showed that the distribution of the fluctuation within the cerebellum neuronal network on a scale from 1 micrometer to 0.1 millimeters follows the same progression of the distribution of matter in the cosmic web,” he added, “but, of course, on a larger scale that goes from 5 million to 500 million light-years.”

The clustering and number of connections emanating from each node also were oddly similar.

“Once again, structural parameters have identified unexpected agreement levels,” Feletti said in the statement. “Probably, the connectivity within the two networks evolves following similar physical principles, despite the striking and obvious difference between the physical powers regulating galaxies and neurons.”

The team is hoping that their preliminary study could lead to new analysis techniques in both cosmology and neurosurgery, allowing scientists to better understand how these structures have evolved over time.